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Understanding Mpox: A rising concern

Aug 26, 2024

Overview
Mpox, previously known as monkeypox, is a viral disease caused by the monkeypox virus, part of the Orthopoxvirus genus, which includes the smallpox virus. Although it was first discovered in monkeys, mpox can infect humans, typically through direct contact with infected animals or individuals. While mpox is less severe than smallpox, it can still lead to significant health challenges, particularly for those with weakened immune systems.

Symptoms
Symptoms of mpox usually manifest between 5 to 21 days after exposure and can persist for 2 to 4 weeks. The illness often begins with flu-like symptoms, including:

  • Fever
  • Headache
  • Muscle aches
  • Backache
  • Swollen lymph nodes
  • Chills
  • Exhaustion

A rash, often starting on the face and spreading to other parts of the body, follows these initial symptoms. The rash undergoes several stages, including macules, papules, vesicles, pustules, and finally scabs. The appearance of these lesions is a hallmark of mpox and helps differentiate it from other illnesses.

Prevention
Preventing the spread of mpox involves several key measures:

  • Vaccination: The smallpox vaccine provides some protection against mpox. Additionally, specific vaccines like Jynneos (also known as Imvamune or Imvanex) have been developed to protect against monkeypox.
  • Avoiding Contact: It’s essential to avoid direct contact with animals that may carry the virus, especially in regions where mpox is common, and to steer clear of individuals who are infected.
  • Hygiene: Regular hand washing with soap and water, or using alcohol-based hand sanitizers, is crucial in preventing the spread of the virus.
  • Protective Gear: Healthcare workers and those in close contact with infected individuals should wear personal protective equipment (PPE) to reduce the risk of transmission.

Treatment
Currently, there is no specific cure for mpox, but several supportive care measures can help manage the symptoms:

  • Antiviral Medication: In severe cases, antiviral drugs like tecovirimat (TPOXX) may be prescribed to reduce the severity of the illness.
  • Symptom Management: Pain relievers, fever reducers, and adequate hydration are essential in managing the symptoms and supporting recovery.
  • Isolation: Infected individuals should be isolated to prevent the virus from spreading to others.

Most people with mpox recover without the need for extensive medical intervention, but monitoring and supportive care are vital to prevent complications.

Climate Change and Mpox: A Potential Link The ongoing effects of climate change may have a role in the spread and frequency of mpox outbreaks. As global temperatures rise, ecosystems and habitats are disrupted, leading to increased human-wildlife interactions. These interactions heighten the risk of zoonotic diseases like mpox being transmitted from animals to humans.

Moreover, climate change can lead to the expansion of habitats for various animals, including those that may carry the monkeypox virus. Deforestation, urbanization, and agricultural expansion also push humans into closer contact with wildlife, increasing the chances of disease spillover events. Additionally, extreme weather events and changes in environmental conditions can stress wildlife populations, potentially making them more susceptible to infections, which in turn can increase the likelihood of transmission to humans.

While more research is needed to fully understand the connection between climate change and mpox, it’s clear that the broader impacts of environmental changes are contributing to the emergence and re-emergence of infectious diseases globally.

Conclusion
Mpox is a re-emerging infectious disease that demands attention due to its potential health impacts, particularly in vulnerable populations. Understanding its symptoms, prevention methods, and treatment options is crucial in managing and reducing the spread of this virus. As with many infectious diseases, education and proactive measures are the best defences in protecting public health.